Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.41 |
| ▸ | COMT | P21964 | 2/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26213657 | 1.00 | HCAR2 (0.41) | HCAR2COMTSPRPTGDR2HTR2B | |
| SCHEMBL30269813 | 0.88 | COMT (0.41) | HCAR2COMTSPRPTGDR2HTR2B | |
| SCHEMBL26213669 | 0.81 | HCAR2 (0.37) | HCAR2COMTSPRPTGDR2 | |
| SCHEMBL32162354 | 0.79 | HCAR2 (0.48) | HCAR2HTR1ASLC6A2SLC6A4 | |
| SCHEMBL2460605 | 0.79 | HCAR2 (0.48) | HCAR2HTR1ASLC6A2SLC6A4 | |
| SCHEMBL26214485 | 0.79 | KIT (0.40) | HCAR2COMTSPRPTGDR2 | |
| SCHEMBL23235688 | 0.77 | HCAR2 (0.47) | HCAR2SPR | |
| SCHEMBL13361555 | 0.76 | HCAR2 (0.46) | HCAR2HTR1ASLC6A2SLC6A4 | |
| SCHEMBL3319484 | 0.75 | KDM4E (0.48) | SPR | |
| SCHEMBL7710106 | 0.74 | HCAR2 (0.44) | HCAR2SPRHTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843271-B | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2024-08-13 | — | — | CN | disclosed |
| CN-115843271-A | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2023-03-24 | — | — | CN | disclosed |