SCHEMBL3027178

SCHEMBL3027178

NCC1[CH]C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4506588 1.00
SCHEMBL17768521 1.00
SCHEMBL9299059 0.72
SCHEMBL17878151 0.67
SCHEMBL6134426 0.65
SCHEMBL6135159 0.64
SCHEMBL1149443 0.64
SCHEMBL7703926 0.62
SCHEMBL8700903 0.61
SCHEMBL527663 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3221300-B1 ANTIBACTERIAL BENZOTHIAZOLE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2019-03-20 EP claimed
EP-3143007-B1 ANTIBACTERIAL QUINAZOLINE-4(3H)-ONE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2018-07-11 EP claimed
EP-3044211-B1 ANTIBACTERIAL 2H-INDAZOLE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2018-01-03 EP claimed
US-20170355687-A1 ANTIBACTERIAL BENZOTHIAZOLE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2017-12-14 US claimed
US-9802901-B2 Antibacterial 2H-indazole derivatives IDORSIA PHARMACEUTICALS LTD (CH) 2017-10-31 US claimed
US-9796686-B2 Antibacterial quinazoline-4(3H)-one derivatives IDORSIA PHARMACEUTICALS LTD (CH) 2017-10-24 US claimed
US-20170081292-A1 ANTIBACTERIAL QUINAZOLINE-4(3H)-ONE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2017-03-23 US claimed
EP-3143007-A1 ANTIBACTERIAL QUINAZOLINE-4(3H)-ONE DERIVATIVES Actelion Pharmaceuticals Ltd (CH) 2017-03-22 EP claimed
US-20160221959-A1 ANTIBACTERIAL 2H-INDAZOLE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2016-08-04 US claimed
EP-3044211-A1 ANTIBACTERIAL 2H-INDAZOLE DERIVATIVES Actelion Pharmaceuticals Ltd (CH) 2016-07-20 EP claimed
WO-2015173329-A1 ANTIBACTERIAL QUINAZOLINE-4(3H)-ONE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2015-11-19 WO claimed
WO-2015036964-A1 ANTIBACTERIAL 2H-INDAZOLE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2015-03-19 WO claimed
CN-114630823-A GLP-1R modulating compounds 吉利德科学公司 2022-06-14 CN disclosed
EP-3344630-B1 SUBSTITUTED 1,2-DIHYDRO-3H-PYRROLO[1,2-C]IMIDAZOL-3-ONE ANTIBACTERIAL COMPOUNDS IDORSIA PHARMACEUTICALS LTD (CH) 2020-12-09 EP disclosed
CN-108026100-B Substituted 1, 2-dihydro-3H-pyrrolo [1,2-c ] imidazol-3-one antibacterial agents 爱杜西亚药品有限公司 2020-09-18 CN disclosed
US-20190315731-A1 6-(BUTA-1,3-DIYN-1-YL)BENZO[D]THIAZOLE DERIVATIVES ACTELION PHARMACEUTICALS, LTD. (CH) 2019-10-17 US disclosed
CN-1993339-A Aromatic compound OTSUKA PHARMA CO LTD (JP) 2007-07-04 CN disclosed
EP-1773797-A2 AROMATIC COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-04-18 EP disclosed
WO-2006014012-A2 AROMATIC COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-02-09 WO disclosed
US-20040167131-A1 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade PFIZER INC. 2004-08-26 US disclosed