Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 7/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.44 |
| ▸ | MDM4 | O15151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30057736 | 0.89 | PRCP (0.49) | PRCPACEACE2MDM4TP53 | |
| SCHEMBL30744273 | 0.86 | PRCP (0.47) | PRCPACEACE2MDM4TP53 | |
| SCHEMBL30962356 | 0.85 | PRCP (0.46) | PRCPACEACE2MDM4TP53 | |
| SCHEMBL29697676 | 0.84 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL29696658 | 0.84 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL24579222 | 0.84 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL29613906 | 0.84 | ACE (0.58) | ACEACE2LTA4H | |
| SCHEMBL29583278 | 0.83 | ACE (0.51) | PRCPACEACE2LMNA | |
| SCHEMBL24580400 | 0.83 | PRCP (0.52) | PRCPACEACE2MDM4TP53 | |
| SCHEMBL31248559 | 0.82 | MDM4 (0.54) | MDM4TP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448545-B1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | CHEMI SPA (IT) | 2025-08-20 | — | — | EP | claimed |
| US-20250042948-A1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | CHEMI SPA (IT) | 2025-02-06 | — | — | US | claimed |
| EP-4194464-A1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | Chemi SPA (IT) | 2023-06-14 | — | — | EP | claimed |
| EP-4448545-B1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | CHEMI SPA (IT) | 2025-08-20 | — | — | EP | disclosed |
| US-20250042948-A1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | CHEMI SPA (IT) | 2025-02-06 | — | — | US | disclosed |
| EP-4448545-A1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | Chemi SPA (IT) | 2024-10-23 | — | — | EP | disclosed |
| CN-118401540-A | Manufacturing process for the production of linaclotide | 凯米股份公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023110781-A1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | CHEMI SPA (IT) | 2023-06-22 | — | — | WO | disclosed |
| EP-4194464-A1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | Chemi SPA (IT) | 2023-06-14 | — | — | EP | disclosed |
| CN-115746104-A | Preparation method of Bulevirtide | 深圳市健翔生物制药有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115746103-A | Preparation method of Bulevirtide | 深圳市健翔生物制药有限公司 | 2023-03-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250042948-A1 | MANUFACTURING PROCESS FOR THE PRODUCTION OF LINACLOTIDE | LPXN, PDE8A, PDE8B | PRCP 796/4885ACE 1167/4885ACE2 1980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.