Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.68 |
| ▸ | FYN | P06241 | 15/20 | 0.57 |
| ▸ | BRAF | P15056 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16009715 | 0.84 | FYN (0.65) | FYN | |
| SCHEMBL3033429 | 0.82 | MKNK1 (1.00) | MKNK1FYN | |
| SCHEMBL3036919 | 0.80 | MKNK1 (0.58) | MKNK1FYN | |
| SCHEMBL3036494 | 0.79 | MKNK1 (0.60) | MKNK1FYN | |
| SCHEMBL16010360 | 0.79 | PIK3CD (0.52) | MKNK1FYNBRAF | |
| SCHEMBL14609612 | 0.79 | FYN (0.60) | MKNK1FYN | |
| SCHEMBL3031885 | 0.78 | MKNK1 (1.00) | MKNK1FYN | |
| SCHEMBL3042012 | 0.77 | MKNK1 (0.85) | MKNK1FYN | |
| SCHEMBL3033080 | 0.77 | MKNK1 (0.60) | MKNK1FYN | |
| SCHEMBL13223364 | 0.77 | NTRK1 (0.64) | MKNK1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216798-A1 | FUSED HETEROCYCLES AS LCK INHIBITORS | ASTELLAS PHARMA INC (JP) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216798-A1 | FUSED HETEROCYCLES AS LCK INHIBITORS | LCK, ZAP70, FYN | MKNK1 816/4885FYN 3/4885BRAF 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.