Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.39 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25034891 | 1.00 | CRBN (0.48) | CRBNDDB1SMARCA2SMARCA4IKZF2 | |
| SCHEMBL25036249 | 0.94 | DDB1 (0.45) | CRBNDDB1SMARCA2SMARCA4IKZF2 | |
| SCHEMBL25036237 | 0.92 | DDB1 (0.45) | CRBNDDB1SMARCA2SMARCA4IKZF2 | |
| SCHEMBL23540956 | 0.87 | CRBN (0.63) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL31160719 | 0.87 | CRBN (0.63) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL22502622 | 0.87 | CRBN (0.63) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL27178974 | 0.86 | CRBN (0.62) | CRBNDDB1IKZF2IKZF3 | |
| SCHEMBL25036927 | 0.84 | DDB1 (0.48) | CRBNDDB1IKZF2IKZF3ALDH1A1 | |
| SCHEMBL23540792 | 0.84 | DDB1 (0.48) | CRBNDDB1IKZF2 | |
| SCHEMBL23541104 | 0.84 | DDB1 (0.48) | CRBNDDB1IKZF2IKZF3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |