Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 19/20 | 0.70 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.57 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.57 |
| ▸ | KDM6B | O15054 | 2/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.53 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.53 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | VEGFA | P15692 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | ASPH | Q12797 | 1/20 | 0.50 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.50 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.50 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.50 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.50 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523711 | 1.00 | EGLN1 (0.70) | EGLN1FTOBBOX1KDM6BKDM4C | |
| SCHEMBL27735216 | 0.86 | EGLN1 (0.53) | EGLN1FTOBBOX1KDM6BKDM4C | |
| SCHEMBL14649383 | 0.85 | EGLN1 (0.73) | EGLN1FTOBBOX1EGLN3VEGFA | |
| SCHEMBL522880 | 0.82 | EGLN1 (0.73) | EGLN1FTOBBOX1EGLN3TET3 | |
| SCHEMBL522241 | 0.81 | EGLN1 (0.57) | EGLN1FTOBBOX1KDM6BKDM4C | |
| SCHEMBL821293 | 0.80 | EGLN1 (0.68) | EGLN1FTOBBOX1KDM6BEGLN3 | |
| SCHEMBL31501044 | 0.80 | EGLN1 (0.68) | EGLN1FTOBBOX1KDM6BEGLN3 | |
| SCHEMBL1219109 | 0.80 | EGLN1 (0.65) | EGLN1FTOBBOX1ASPHKDM8 | |
| SCHEMBL1269099 | 0.80 | EGLN1 (0.61) | EGLN1FTOKDM6BKDM4CKDM5B | |
| SCHEMBL4070258 | 0.79 | EGLN1 (0.68) | EGLN1FTOBBOX1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4142721-A1 | HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE INHIBITORS FOR TREATING AGING-RELATED CONDITIONS | Bioage Labs, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |