SCHEMBL30274591

SCHEMBL30274591

O=C(O)CNC(=O)c1nc(-c2ccoc2)c2ccsc2c1O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 17/20 0.43
FTO Q9C0B1 2/20 0.42
BBOX1 O75936 1/20 0.42
ADORA2A P29274 2/20 0.41
ADORA1 P30542 2/20 0.41
LRRK2 Q5S007 1/20 0.38
KDM5B Q9UGL1 1/20 0.37
KDM2A Q9Y2K7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL964901 1.00 EGLN1 (0.43) EGLN1FTOBBOX1ADORA2AADORA1
SCHEMBL967119 0.92 EGLN1 (0.45) EGLN1FTOBBOX1ADORA2AADORA1
SCHEMBL966064 0.85 EGLN1 (0.52) EGLN1FTOBBOX1KDM5BKDM2A
SCHEMBL969028 0.83 EGLN1 (0.60) EGLN1FTOBBOX1
SCHEMBL967989 0.83 EGLN1 (0.44) EGLN1FTOBBOX1KDM5BKDM2A
SCHEMBL965224 0.81 EGLN1 (0.45) EGLN1FTOBBOX1ADORA2AADORA1
SCHEMBL969100 0.79 EGLN1 (0.47) EGLN1FTOBBOX1
SCHEMBL30274587 0.78 EGLN1 (0.64) EGLN1FTOBBOX1KDM5BKDM2A
SCHEMBL968184 0.78 EGLN1 (0.64) EGLN1FTOBBOX1KDM5BKDM2A
SCHEMBL967787 0.77 EGLN1 (0.60) EGLN1FTOBBOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4142721-A1 HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE INHIBITORS FOR TREATING AGING-RELATED CONDITIONS Bioage Labs, Inc. (US) 2023-03-08 EP disclosed