Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 13/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21383675 | 1.00 | PTPN11 (0.37) | PTPN11HTR2AKCNH2DPP9DPP7 | |
| SCHEMBL29352364 | 1.00 | PTPN11 (0.37) | PTPN11HTR2AKCNH2DPP9DPP7 | |
| SCHEMBL21383761 | 1.00 | PTPN11 (0.37) | PTPN11HTR2AKCNH2DPP9DPP7 | |
| SCHEMBL22493782 | 1.00 | PTPN11 (0.37) | PTPN11HTR2AKCNH2DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL31033471 | 0.98 | PTPN11 (0.36) | PTPN11HTR2AKCNH2DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL21383746 | 0.98 | PTPN11 (0.36) | PTPN11HTR2AKCNH2DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL28960494 | 0.98 | PTPN11 (0.36) | PTPN11HTR2AKCNH2DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL21383835 | 0.98 | PTPN11 (0.36) | PTPN11HTR2AKCNH2DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL21384023 | 0.98 | PTPN11 (0.36) | PTPN11HTR2AKCNH2DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL30529389 | 0.98 | PTPN11 (0.36) | PTPN11HTR2AKCNH2DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874363-B | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-117263942-A | SHP2 phosphatase inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-112166110-B | SHP2 phosphatase inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-115734966-A | Heterocyclic compounds and their use | 石药集团中奇制药技术（石家庄）有限公司 | 2023-03-03 | — | — | CN | disclosed |