SCHEMBL3027855

SCHEMBL3027855

CCC(Oc1ccc(SC/C=C(/I)c2ccc(C(F)(F)F)cc2)cc1C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 18/20 0.47
PPARA Q07869 4/20 0.47
PTGDR2 Q9Y5Y4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3027857 1.00 PPARD (0.47) PPARDPPARAPTGDR2
SCHEMBL3027851 1.00 PPARD (0.47) PPARDPPARAPTGDR2
SCHEMBL3031949 0.87 PPARD (0.54) PPARDPPARAPTGDR2
SCHEMBL3031946 0.87 PPARD (0.54) PPARDPPARAPTGDR2
SCHEMBL657163 0.87 PPARA (0.49) PPARDPPARA
SCHEMBL657164 0.87 PPARA (0.49) PPARDPPARA
SCHEMBL3270484 0.82 PPARD (0.63) PPARDPPARA
SCHEMBL3270480 0.82 PPARD (0.63) PPARDPPARA
SCHEMBL3270475 0.82 PPARD (0.63) PPARDPPARA
SCHEMBL3030622 0.80 PPARD (0.50) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100210653-A1 Novel Compounds, Their Preparations and Use HIGH POINT PHARMACEUTICALS, LLC (US) 2010-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210653-A1 Novel Compounds, Their Preparations and Use PPARG, PPARD, PPARA PPARD 2/4885PPARA 3/4885PTGDR2 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.