Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | THRB | P10828 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | KDR | P35968 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MTOR | P42345 | 1/20 | 0.67 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028329 | 0.86 | KDR (1.00) | MAPTPOLBTHRBHTTALDH1A1 | |
| SCHEMBL15783186 | 0.82 | KDR (0.81) | MAPTPOLBTHRBHTTALDH1A1 | |
| SCHEMBL2211831 | 0.82 | MAPT (1.00) | MAPTPOLBTHRBHTTALDH1A1 | |
| SCHEMBL3024303 | 0.82 | MAPT (1.00) | MAPTPOLBTHRBHTTALDH1A1 | |
| SCHEMBL7918628 | 0.81 | MAPT (0.81) | MAPTPOLBTHRBHTTALDH1A1 | |
| SCHEMBL3021512 | 0.81 | MAPT (0.81) | MAPTPOLBTHRBHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL1396134 | 0.81 | MAPT (0.97) | MAPTPOLBTHRBHTTALDH1A1 | |
| SCHEMBL3028283 | 0.81 | MAPT (0.67) | MAPTPOLBTHRBHTTALDH1A1 | |
| SCHEMBL14235459 | 0.81 | KDR (0.78) | MAPTTHRBHTTALDH1A1L3MBTL1 | |
| SCHEMBL23493840 | 0.80 | MAPT (1.00) | MAPTPOLBTHRBKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9316633-B2 | Methods for identifying inhibitors of solute transporters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-04-19 | — | — | US | disclosed |
| US-20100190796-A1 | METHODS FOR IDENTIFYING INHIBITORS OF SOLUTE TRANSPORTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190796-A1 | METHODS FOR IDENTIFYING INHIBITORS OF SOLUTE TRANSPORTERS | SLC2A1, SLC2A3, SLC2A8 | MAPT 1849/4885POLB 3051/4885THRB 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.