Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.68 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.68 |
| ▸ | ITGAL | P20701 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978957 | 1.00 | ITGB2 (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL26107630 | 1.00 | ITGB2 (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL23978578 | 1.00 | ITGB2 (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL23978626 | 0.95 | ITGB2 (0.70) | ITGB2ICAM1ITGAL | |
| SCHEMBL23978966 | 0.95 | ITGB2 (0.70) | ITGB2ICAM1ITGAL | |
| SCHEMBL26476126 | 0.93 | ITGB2 (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL26476218 | 0.93 | ITGB2 (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL30279383 | 0.93 | ITGB2 (0.74) | ITGB2ICAM1ITGAL | |
| SCHEMBL23978571 | 0.93 | ITGB2 (0.74) | ITGB2ICAM1ITGAL | |
| SCHEMBL23978604 | 0.93 | ITGB2 (0.74) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |
| EP-4142707-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2023-03-08 | — | — | EP | disclosed |