Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18605019 | 1.00 | KLKB1 (0.83) | KLKB1 | |
| SCHEMBL22975984 | 0.94 | KLKB1 (0.83) | KLKB1 | |
| SCHEMBL30279508 | 0.91 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL18604943 | 0.91 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL22394344 | 0.90 | KLKB1 (0.68) | KLKB1 | |
| SCHEMBL29825699 | 0.90 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL18604666 | 0.90 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL18632075 | 0.88 | KLKB1 (0.81) | KLKB1 | |
| SCHEMBL18604908 | 0.87 | KLKB1 (0.84) | KLKB1 | |
| SCHEMBL23119614 | 0.86 | KLKB1 (0.65) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230100082-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230100082-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | KLKB1, KLK5, KLK1 | KLKB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.