Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25153357 | 1.00 | ABL1 (0.41) | ABL1BRD4LMNAALDH1A1AURKA | |
| SCHEMBL25153266 | 0.83 | BRD4 (0.50) | ABL1BRD4LMNAALDH1A1AURKA | |
| SCHEMBL30280433 | 0.83 | BRD4 (0.50) | ABL1BRD4LMNAALDH1A1AURKA | |
| SCHEMBL16537462 | 0.77 | ABL1 (0.51) | ABL1BRD4LMNAALDH1A1AURKA | |
| SCHEMBL30731119 | 0.73 | ABL1 (0.37) | ABL1BRD4LMNAALDH1A1AURKA | |
| SCHEMBL22554256 | 0.73 | ABL1 (0.37) | ABL1BRD4LMNAALDH1A1AURKA | |
| SCHEMBL25153572 | 0.72 | GCK (0.38) | ABL1BRD4LMNAALDH1A1AURKA | |
| SCHEMBL30280442 | 0.72 | GCK (0.38) | ABL1BRD4LMNAALDH1A1AURKA | |
| SCHEMBL25153355 | 0.72 | CHEK1 (0.37) | ABL1LMNAALDH1A1AURKADAPK3 | |
| SCHEMBL25153360 | 0.72 | CHEK1 (0.37) | ABL1LMNAALDH1A1AURKADAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064218-A1 | TYRO3 INHIBITORS | Halia Therapeutics, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |