Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280401 | 0.94 | PTPN11 (0.45) | PTPN11MAOAMAOBCHEK1CHEK2 | |
| SCHEMBL30280423 | 0.94 | PTPN11 (0.43) | PTPN11MAOAMAOBCHEK1CHEK2 | |
| SCHEMBL30280479 | 0.91 | PTPN11 (0.46) | PTPN11CHEK1KCNH2MAPK1HTR6 | |
| SCHEMBL31396631 | 0.91 | PTPN11 (0.45) | PTPN11MAOAMAOBCHEK1KCNH2 | |
| SCHEMBL31396598 | 0.91 | PTPN11 (0.45) | PTPN11CHEK1KCNH2MAPK1HTR6 | |
| SCHEMBL31396546 | 0.88 | PTPN11 (0.47) | PTPN11CHEK1KCNH2CD274HTR6 | |
| SCHEMBL31396592 | 0.86 | PTPN11 (0.48) | PTPN11CHEK1KCNH2CD274HTR6 | |
| SCHEMBL31396601 | 0.86 | PTPN11 (0.48) | PTPN11CHEK1KCNH2HTR6KDR | |
| SCHEMBL31396593 | 0.86 | PTPN11 (0.49) | PTPN11CHEK1KCNH2HTR6KDR | |
| SCHEMBL31396539 | 0.84 | PTPN11 (0.49) | PTPN11CHEK1KCNH2KDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064218-A1 | TYRO3 INHIBITORS | Halia Therapeutics, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |