SCHEMBL30280776

SCHEMBL30280776

Cc1cc(C2CCC2)c(C(=O)CBr)cc1C(=O)N1CCC(c2ccccc2C#N)CC1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30280934 0.87 FASN (0.49) FASN
SCHEMBL30280939 0.86 FASN (0.78) FASN
SCHEMBL12488110 0.86 FASN (0.78) FASN
SCHEMBL30281041 0.83 FASN (0.55) FASN
SCHEMBL19113241 0.83 FASN (0.53) FASN
SCHEMBL12488882 0.79 FASN (0.67) FASN
SCHEMBL30280954 0.79 FASN (0.67) FASN
SCHEMBL30280978 0.79 FASN (0.52) FASN
SCHEMBL30280913 0.78 FASN (0.77) FASN
SCHEMBL30410302 0.77 FASN (0.59) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116139138-A Heterocyclic modulators of lipid synthesis 3-V生物科学股份有限公司 2023-05-23 CN disclosed
CN-110177551-B Heterocyclic modulators of lipid synthesis 3-V生物科学股份有限公司 2023-02-17 CN disclosed