SCHEMBL30280892

SCHEMBL30280892

CCc1nnc(-c2cc(C(=O)N3CCC(c4ccccc4C#N)CC3)c(C)cc2C2CC(F)(F)C2)[nH]1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30280932 0.92 FASN (0.60) FASN
SCHEMBL30280807 0.90 FASN (0.51) FASN
SCHEMBL12489215 0.88 FASN (0.76) FASN
SCHEMBL30410061 0.86 FASN (0.57) FASN
SCHEMBL30280832 0.85 FASN (0.58) FASN
SCHEMBL30281101 0.85 FASN (0.58) FASN
SCHEMBL30280723 0.85 FASN (0.50) FASN
SCHEMBL30408605 0.85 FASN (0.55) FASN
SCHEMBL30280810 0.84 FASN (0.59) FASN
SCHEMBL30281016 0.84 FASN (0.59) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116139138-A Heterocyclic modulators of lipid synthesis 3-V生物科学股份有限公司 2023-05-23 CN disclosed
CN-110177551-B Heterocyclic modulators of lipid synthesis 3-V生物科学股份有限公司 2023-02-17 CN disclosed