SCHEMBL30280894

SCHEMBL30280894

CCc1cc(C)c(C(=O)N2CCC(c3ccccc3C#N)CC2)cc1-c1nnc(CCOC)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30280835 0.94 FASN (0.57) FASN
SCHEMBL30281047 0.94 FASN (0.57) FASN
SCHEMBL30280861 0.94 FASN (0.56) FASN
SCHEMBL30280948 0.93 FASN (0.59) FASN
SCHEMBL30280970 0.92 FASN (0.58) FASN
SCHEMBL30280896 0.92 FASN (0.62) FASN
SCHEMBL30280944 0.92 FASN (0.58) FASN
SCHEMBL30280933 0.91 FASN (0.60) FASN
SCHEMBL30280921 0.90 FASN (0.59) FASN
SCHEMBL30280816 0.89 FASN (0.58) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116139138-A Heterocyclic modulators of lipid synthesis 3-V生物科学股份有限公司 2023-05-23 CN disclosed
CN-110177551-B Heterocyclic modulators of lipid synthesis 3-V生物科学股份有限公司 2023-02-17 CN disclosed