Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047935 | 1.00 | PTGER4 (0.40) | PTGER4HTTCTSVCTSLCTSS | |
| SCHEMBL30284472 | 0.88 | MAPT (0.32) | PTGER4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31691678 | 0.85 | SCN9A (0.37) | PTGER4CTSLCTSSCTSBCTSK | |
| SCHEMBL29047942 | 0.84 | PTGER4 (0.39) | PTGER4HTTCTSVCTSLCTSS | |
| SCHEMBL30284379 | 0.84 | PTGER4 (0.39) | PTGER4HTTCTSVCTSLCTSS | |
| SCHEMBL29047941 | 0.82 | CYP1A2 (0.34) | PTGER4HTTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29047938 | 0.79 | PTGER4 (0.37) | PTGER4HTTCTSVCTSLCTSS | |
| SCHEMBL30284402 | 0.79 | PTGER4 (0.37) | PTGER4HTTCTSVCTSLCTSS | |
| SCHEMBL26195067 | 0.78 | HTR2A (0.35) | PTGER4HTTCTSVCTSLCTSS | |
| SCHEMBL22116017 | 0.76 | PTGER4 (0.43) | PTGER4HTTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157017-A | 3- (pyridazin-4-yl) -5, 6-dihydro-4H-1, 2, 4-oxadiazine derivatives as fungicides for crop protection | 拜耳公司 | 2023-05-23 | — | — | CN | disclosed |
| EP-4168404-A1 | 3-(PYRIDAZIN-4-YL)-5,6-DIHYDRO-4H-1,2,4-OXADIAZINE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION | Bayer Aktiengesellschaft (DE) | 2023-04-26 | — | — | EP | disclosed |