Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 17/20 | 0.67 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.62 |
| ▸ | CDK2 | P24941 | 2/20 | 0.62 |
| ▸ | CCNK | O75909 | 1/20 | 0.62 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.62 |
| ▸ | CCR7 | P32248 | 2/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26461000 | 1.00 | CCR6 (0.67) | CCR6CCNA2CDK2CCNKCDK12 | |
| SCHEMBL30284901 | 0.95 | CCR6 (0.62) | CCR6CCNA2CDK2CCNKCDK12 | |
| SCHEMBL26461008 | 0.95 | CCR6 (0.62) | CCR6CCNA2CDK2CCNKCDK12 | |
| SCHEMBL25079459 | 0.89 | CCR6 (0.68) | CCR6CCNA2CDK2CCNKCDK12 | |
| SCHEMBL30284786 | 0.89 | CCR6 (0.68) | CCR6CCNA2CDK2CCNKCDK12 | |
| SCHEMBL26527123 | 0.88 | CCR6 (0.51) | CCR6CCNA2CDK2CCNKCDK12 | |
| SCHEMBL25079824 | 0.85 | CCR6 (0.64) | CCR6CCNA2CDK2CCNKCDK12 | |
| SCHEMBL26526137 | 0.85 | CCR6 (0.49) | CCR6CCNA2CDK2CCNKCDK12 | |
| Hydrochloric Acid SCHEMBL30284807 | 0.84 | CCR6 (0.63) | CCR6CCNA2CDK2CCNKCDK12 | |
| SCHEMBL30284788 | 0.84 | CCR6 (0.63) | CCR6CCNA2CDK2CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387965-A2 | ARYL SULFONYL COMPOUNDS AS CCR6 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023023534-A2 | ARYL SULFONYL COMPOUNDS AS CCR6 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |