SCHEMBL30285083

SCHEMBL30285083

CCOC(=O)c1cc(=O)c2ccccc2o1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.80
AKR1B1 P15121 1/20 0.71
GAA P10253 1/20 0.67
MAPT P10636 1/20 0.67
KMT2A Q03164 5/20 0.66
MEN1 O00255 3/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
ATM Q13315 1/20 0.65
TNKS O95271 1/20 0.64
KDM4E B2RXH2 3/20 0.61
LMNA P02545 1/20 0.61
HPGD P15428 1/20 0.61
HSD17B10 Q99714 1/20 0.61
USP2 O75604 1/20 0.60
CSNK2A2 P19784 1/20 0.60
PTGS1 P23219 1/20 0.60
CSNK2B P67870 1/20 0.60
CSNK2A1 P68400 1/20 0.60
CSNK2A3 Q8NEV1 1/20 0.60
RAB9A P51151 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3359780 1.00 MAOB (0.80) MAOBAKR1B1GAAMAPTKMT2A
SCHEMBL31047782 0.99 MAOB (0.78) MAOBAKR1B1GAAMAPTKMT2A
SCHEMBL20876884 0.99 MAOB (0.78) MAOBAKR1B1GAAMAPTKMT2A
SCHEMBL6957297 0.86 MAOB (0.71) MAOBAKR1B1GAAMAPTKMT2A
SCHEMBL27635896 0.85 MAOB (0.83) MAOBAKR1B1GAAMAPTKMT2A
SCHEMBL8117451 0.84 AKR1B1 (0.78) MAOBAKR1B1GAAMAPTKMT2A
SCHEMBL22617461 0.84 MAOB (0.76) MAOBAKR1B1GAAMAPTKMT2A
SCHEMBL8827849 0.84 AKR1B1 (0.78) MAOBAKR1B1GAAMAPTKMT2A
SCHEMBL3397825 0.83 MAPT (0.68) MAOBGAAMAPTKMT2AMEN1
SCHEMBL29463595 0.83 MAPT (0.68) MAOBGAAMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311813-B Palladium-catalyzed meta-C-H functionalized universal ligands 斯克利普斯研究院 2023-02-28 CN disclosed