Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 13/20 | 0.56 |
| ▸ | PARP11 | Q9NR21 | 9/20 | 0.56 |
| ▸ | PARP1 | P09874 | 6/20 | 0.56 |
| ▸ | F7 | P08709 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 4/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21333738 | 1.00 | PARP10 (0.56) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL19887445 | 0.93 | PARP10 (0.56) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL793729 | 0.85 | PARP10 (0.62) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL27086102 | 0.82 | NTRK2 (0.47) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL24039931 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL30800588 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL20572003 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL14991814 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL23865194 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1F7F3 | |
| SCHEMBL15471838 | 0.79 | PARP10 (0.56) | PARP10PARP11PARP1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825656-B | Inhibitors of protein arginine methyltransferase 5 (PRMT 5), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2023-03-31 | — | — | CN | disclosed |