Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL302855 | 0.85 | PTGDR2 (0.41) | BRD4BRD9 | |
| SCHEMBL303311 | 0.69 | PTGDR2 (0.43) | BRD4BRD9 | |
| SCHEMBL302466 | 0.68 | AR (0.34) | BRD4BRD9 | |
| SCHEMBL303148 | 0.68 | JAK2 (0.44) | BRD4BRD9 | |
| SCHEMBL304286 | 0.68 | P2RY1 (0.38) | BRD4BRD9 | |
| SCHEMBL304178 | 0.67 | P2RY1 (0.38) | BRD4BRD9 | |
| SCHEMBL304351 | 0.67 | CARM1 (0.38) | BRD4BRD9 | |
| SCHEMBL21819922 | 0.66 | CARM1 (0.49) | — | |
| SCHEMBL1921911 | 0.66 | JAK2 (0.37) | BRD4BRD9 | |
| SCHEMBL303279 | 0.66 | CARM1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500853-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2328871-A2 | HEDGEHOG PATHWAY MODULATORS | IRM LLC (BM) | 2011-06-08 | — | — | EP | claimed |
| WO-2010027746-A2 | HEDGEHOG PATHWAY MODULATORS | IRM LLC (BM) | 2010-03-11 | — | — | WO | claimed |