Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 6/20 | 0.74 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26186537 | 1.00 | P2RX4 (0.74) | P2RX4ANO1RECQLSMN1; SMN2LMNA | |
| SCHEMBL25371053 | 0.92 | P2RX4 (0.81) | P2RX4ANO1RECQLSMN1; SMN2LMNA | |
| SCHEMBL26186490 | 0.89 | P2RX4 (0.72) | P2RX4ANO1RECQLSMN1; SMN2LMNA | |
| SCHEMBL25371065 | 0.89 | P2RX4 (0.69) | P2RX4ANO1 | |
| SCHEMBL25371920 | 0.89 | P2RX4 (0.69) | P2RX4ANO1RECQLSMN1; SMN2LMNA | |
| SCHEMBL25371181 | 0.89 | P2RX4 (0.74) | P2RX4ANO1RECQLSMN1; SMN2LMNA | |
| SCHEMBL30285836 | 0.89 | P2RX4 (0.77) | P2RX4ANO1RECQLSMN1; SMN2LMNA | |
| SCHEMBL30285760 | 0.89 | P2RX4 (0.74) | P2RX4ANO1RECQLSMN1; SMN2LMNA | |
| SCHEMBL26186546 | 0.89 | P2RX4 (0.77) | P2RX4ANO1RECQLSMN1; SMN2LMNA | |
| SCHEMBL26186541 | 0.89 | P2RX4 (0.74) | P2RX4ANO1RECQLSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | claimed |
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115989218-A | Use of N-phenylacetamides having P2X4 receptor antagonistic activity for the treatment of certain eye diseases | 拜耳公司 | 2023-04-18 | — | — | CN | disclosed |