Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25187217 | 1.00 | CYP2D6 (0.41) | CYP2D6TSHRALDH1A1NOTUMGHSR | |
| SCHEMBL25187515 | 0.97 | CYP2D6 (0.40) | CYP2D6TSHRALDH1A1NOTUMGHSR | |
| SCHEMBL30287233 | 0.97 | CYP2D6 (0.40) | CYP2D6TSHRALDH1A1NOTUMGHSR | |
| SCHEMBL25190015 | 0.92 | TSHR (0.42) | CYP2D6TSHRALDH1A1NOTUMGHSR | |
| SCHEMBL25189753 | 0.91 | CYP2D6 (0.41) | CYP2D6TSHRALDH1A1NOTUMGHSR | |
| SCHEMBL30287263 | 0.89 | TSHR (0.40) | CYP2D6TSHRALDH1A1NOTUMGHSR | |
| SCHEMBL25743458 | 0.89 | TSHR (0.40) | CYP2D6TSHRALDH1A1NOTUMGHSR | |
| SCHEMBL23943610 | 0.89 | TSHR (0.40) | CYP2D6TSHRALDH1A1NOTUMGHSR | |
| SCHEMBL25187275 | 0.88 | CYP2D6 (0.39) | CYP2D6TSHRALDH1A1NOTUMGHSR | |
| SCHEMBL25187880 | 0.87 | NOTUM (0.41) | CYP2D6TSHRNOTUMGHSRGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969937-A | BCL-2 inhibitors | 百济神州有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116969936-A | BCL-2 inhibitors | 百济神州有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116802179-A | BCL-2 inhibitors | 百济神州有限公司 | 2023-09-22 | — | — | CN | disclosed |
| EP-4136084-A1 | BCL-2 INHIBITOR | BeiGene, Ltd. (KY) | 2023-02-22 | — | — | EP | disclosed |