⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287173 | 0.79 | — | — | |
| SCHEMBL4219834 | 0.77 | — | — | |
| SCHEMBL16166922 | 0.77 | — | — | |
| SCHEMBL21633906 | 0.77 | — | — | |
| SCHEMBL11232332 | 0.77 | — | — | |
| SCHEMBL19225690 | 0.75 | — | — | |
| SCHEMBL11658193 | 0.73 | GABRR1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL31482565 | 0.73 | EPHX1 (0.31) | — | |
| SCHEMBL15808491 | 0.73 | — | — | |
| SCHEMBL7052237 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210864-A1 | PROCESS FOR THE PREPARATION OF N-ARYLMORPHOLINONES | DORSCH DIETER | 2010-08-19 | — | — | US | disclosed |
| US-7687624-B2 | Process for the production of N-arylmorpholinones | MERCK PATENT GMBH (DE) | 2010-03-30 | — | — | US | disclosed |
| US-20060217550-A1 | One pot process; cyclization; 4-(4-nitrophenyl)-3-oxomorpholine; Factor Xa inhibitors; , myocardial infarction, arteriosclerosis, inflammation, apoplexy, angina pectoris, restenosis after angioplasty and claudicatio intermittens | MERCK PATENT GMBH (DE) | 2006-09-28 | — | — | US | disclosed |