Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288446 | 1.00 | MAPT (0.45) | MAPTCYP3A4HTR6HTR2AHTR2C | |
| SCHEMBL15701952 | 0.83 | MAPT (0.63) | MAPTCYP3A4HTR6HTR2AHTR2C | |
| SCHEMBL23083004 | 0.83 | MAPT (0.63) | MAPTCYP3A4HTR6HTR2AHTR2C | |
| SCHEMBL30288464 | 0.81 | MAPT (0.45) | MAPTCYP3A4HTR6HTR2AHTR2C | |
| SCHEMBL30288449 | 0.81 | MAPT (0.45) | MAPTCYP3A4HTR6HTR2AHTR2C | |
| SCHEMBL15701932 | 0.81 | MAPT (0.45) | MAPTCYP3A4HTR6HTR2AHTR2C | |
| SCHEMBL30288457 | 0.81 | SLC6A2 (0.49) | MAPTCYP3A4HTR6HTR2AHTR2C | |
| SCHEMBL30288456 | 0.81 | SLC6A2 (0.49) | MAPTCYP3A4HTR6HTR2AHTR2C | |
| SCHEMBL30288452 | 0.78 | TAAR1 (0.43) | MAPTCYP3A4HTR6ALDH1A1TSHR | |
| SCHEMBL30288469 | 0.78 | TAAR1 (0.43) | MAPTCYP3A4HTR6ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146198-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | Psilera Inc. (US) | 2023-03-15 | — | — | EP | claimed |
| EP-4146198-A1 | NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS | Psilera Inc. (US) | 2023-03-15 | — | — | EP | disclosed |