Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289469 | 1.00 | DDB1 (0.54) | DDB1CRBN | |
| SCHEMBL23832613 | 0.89 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL22776694 | 0.87 | DDB1 (0.57) | DDB1CRBN | |
| SCHEMBL30288997 | 0.87 | DDB1 (0.51) | DDB1CRBN | |
| SCHEMBL30289147 | 0.87 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL30288978 | 0.87 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL26098625 | 0.86 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL30289087 | 0.86 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL30288925 | 0.86 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL24764449 | 0.86 | DDB1 (0.55) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4405359-A2 | MDM2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023049790-A2 | MDM2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-03-30 | — | — | WO | disclosed |