Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 13/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.64 |
| ▸ | STAT3 | P40763 | 5/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392669 | 0.99 | DDB1 (0.65) | DDB1CRBNSTAT3HRH3 | |
| SCHEMBL26099555 | 0.99 | DDB1 (0.65) | DDB1CRBNSTAT3HRH3 | |
| SCHEMBL26100185 | 0.99 | DDB1 (0.65) | DDB1CRBNSTAT3HRH3 | |
| SCHEMBL21070729 | 0.96 | DDB1 (0.70) | DDB1CRBNSTAT3HRH3 | |
| SCHEMBL29700875 | 0.95 | DDB1 (0.71) | DDB1CRBNSTAT3HRH3 | |
| SCHEMBL20845764 | 0.95 | DDB1 (0.71) | DDB1CRBNSTAT3HRH3 | |
| SCHEMBL20845734 | 0.95 | DDB1 (0.71) | DDB1CRBNSTAT3HRH3 | |
| SCHEMBL20845733 | 0.95 | DDB1 (0.71) | DDB1CRBNSTAT3HRH3 | |
| SCHEMBL29700864 | 0.95 | DDB1 (0.71) | DDB1CRBNSTAT3HRH3 | |
| SCHEMBL20845732 | 0.95 | DDB1 (0.71) | DDB1CRBNSTAT3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4405359-A2 | MDM2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023049790-A2 | MDM2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-03-30 | — | — | WO | disclosed |