Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289052 | 1.00 | ABCB1 (0.46) | ABCB1KLK7FKBP1AMCL1UCHL1 | |
| SCHEMBL30289424 | 1.00 | ABCB1 (0.46) | ABCB1KLK7FKBP1AMCL1UCHL1 | |
| SCHEMBL7279798 | 0.90 | ABCB1 (0.54) | ABCB1KLK7FKBP1AMCL1UCHL1 | |
| SCHEMBL21273903 | 0.90 | ABCB1 (0.54) | ABCB1KLK7FKBP1AMCL1UCHL1 | |
| SCHEMBL1448111 | 0.90 | ABCB1 (0.54) | ABCB1KLK7FKBP1AMCL1UCHL1 | |
| SCHEMBL7703700 | 0.90 | ABCB1 (0.54) | ABCB1KLK7FKBP1AMCL1UCHL1 | |
| SCHEMBL16064932 | 0.85 | ABCB1 (0.47) | ABCB1KLK7FKBP1AMCL1UCHL1 | |
| SCHEMBL15417732 | 0.84 | ABCB1 (0.48) | ABCB1KLK7FKBP1AMCL1UCHL1 | |
| SCHEMBL23491959 | 0.84 | MCL1 (0.51) | ABCB1FKBP1AMCL1 | |
| SCHEMBL6974007 | 0.84 | MCL1 (0.51) | ABCB1FKBP1AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4405359-A2 | MDM2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023049790-A2 | MDM2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-03-30 | — | — | WO | disclosed |