SCHEMBL30291346

SCHEMBL30291346

O=Cc1cccc2c1C=CCO2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2B6 P20813 1/20 0.43
CYP1A2 P05177 7/20 0.41
CYP1B1 Q16678 6/20 0.41
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
CYP1A1 P04798 6/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MTNR1A P48039 2/20 0.36
MTNR1B P49286 1/20 0.36
ERN1 O75460 2/20 0.34
KCNJ1 P48048 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
TRIM24 O15164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13113614 1.00 CYP2B6 (0.43) CYP2B6CYP1A2CYP1B1CA1CA9
SCHEMBL28208426 0.84 MEN1 (0.34) CYP2B6CYP1A2CYP1B1CA1CA9
SCHEMBL275271 0.77 CYP2B6 (0.46) CYP2B6CYP1A2CYP1B1CA1CA9
SCHEMBL30453312 0.75 CA1 (0.36) CYP1A2CYP1B1CA1CA9
SCHEMBL28663419 0.75 CYP2B6 (0.39) CYP2B6CYP1A2CYP1B1CA1CA9
SCHEMBL5541390 0.73 CYP2B6 (0.42) CYP2B6CYP1A2CYP1B1CA1CA9
SCHEMBL14653042 0.73 CYP2B6 (0.42) CYP2B6CYP1A2CYP1B1CA1CA9
SCHEMBL2008458 0.73 CYP2B6 (0.42) CYP2B6CYP1A2CYP1B1CA1CA9
SCHEMBL8215841 0.73 CYP1A2 (0.46) CYP2B6CYP1A2CYP1B1CA1CA9
SCHEMBL5541990 0.73 CYP2B6 (0.46) CYP2B6CYP1A2CYP1B1CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112552309-B Psoralen benzene sulfonate derivative and application thereof 中国科学院新疆理化技术研究所 2023-03-14 CN disclosed