SCHEMBL30293601

SCHEMBL30293601

CC1CCCN1Cc1nc2cc(NC(=O)c3cccnc3)ccc2[nH]1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MLLT1 Q03111 20/20 0.68
MLLT3 P42568 2/20 0.68
CHRM2 P08172 1/20 0.68
PIM1 P11309 1/20 0.68
ACHE P22303 1/20 0.68
SLC6A2 P23975 1/20 0.68
TRIB2 Q92519 1/20 0.68
HRH3 Q9Y5N1 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30293626 1.00 MLLT1 (0.68) MLLT1MLLT3CHRM2PIM1ACHE
SCHEMBL30293563 0.90 MLLT1 (0.65) MLLT1MLLT3CHRM2PIM1ACHE
SCHEMBL24376311 0.90 MLLT1 (0.65) MLLT1MLLT3CHRM2PIM1ACHE
SCHEMBL24376312 0.87 MLLT1 (0.88) MLLT1MLLT3CHRM2PIM1ACHE
SCHEMBL24376332 0.87 MLLT1 (0.62) MLLT1MLLT3CHRM2PIM1ACHE
SCHEMBL29622143 0.87 MLLT1 (0.62) MLLT1MLLT3CHRM2PIM1ACHE
SCHEMBL24376319 0.86 MLLT1 (0.66) MLLT1MLLT3CHRM2PIM1ACHE
SCHEMBL24376342 0.86 MLLT1 (0.65) MLLT1MLLT3CHRM2PIM1ACHE
SCHEMBL24376425 0.86 MLLT1 (0.65) MLLT1MLLT3CHRM2PIM1ACHE
SCHEMBL24376457 0.86 MLLT1 (0.65) MLLT1MLLT3CHRM2PIM1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023038500-A1 COMPOUND FOR DEGRADING ENL PROTEIN AND MEDICAL USES THEREOF 주식회사 유빅스테라퓨틱스 2023-03-16 WO disclosed