Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.68 |
| ▸ | FBP1 | P09467 | 2/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | INSR | P06213 | 1/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.60 |
| ▸ | FLT4 | P35916 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | CLK1 | P49759 | 1/20 | 0.60 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.60 |
| ▸ | TEK | Q02763 | 1/20 | 0.60 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.60 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366535 | 1.00 | EGFR (0.68) | EGFRFBP1ERBB2AURKAINSR | |
| Hydrochloric Acid SCHEMBL8314953 | 0.99 | EGFR (0.67) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL25241 | 0.93 | EGFR (0.63) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL30237488 | 0.93 | EGFR (0.63) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL29615011 | 0.93 | EGFR (0.63) | EGFRFBP1ERBB2AURKAINSR | |
| Hydrochloric Acid SCHEMBL4780920 | 0.92 | EGFR (0.62) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL20305667 | 0.90 | EGFR (0.60) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL18862887 | 0.90 | EGFR (0.60) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL3246075 | 0.90 | EGFR (0.61) | EGFRFBP1ERBB2AURKAINSR | |
| SCHEMBL30113246 | 0.90 | EGFR (0.61) | EGFRFBP1ERBB2AURKAINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041339-A | Afatinib intermediate impurity and preparation method and application thereof | 北京民康百草医药科技有限公司 | 2023-05-02 | — | — | CN | disclosed |