SCHEMBL30294162

SCHEMBL30294162

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 5/20 0.56
▸ KISS1R Q969F8 10/20 0.55
▸ CTSL P07711 3/20 0.52
▸ CTSS P25774 3/20 0.52
▸ CTSK P43235 3/20 0.52
▸ CTSH P09668 1/20 0.52
▸ GRPR P30550 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20046066 1.00 MC4R (0.56) MC4RKISS1RCTSLCTSSCTSK
SCHEMBL20045522 1.00 MC4R (0.56) MC4RKISS1RCTSLCTSSCTSK
SCHEMBL23968026 1.00 MC4R (0.56) MC4RKISS1RCTSLCTSSCTSK
SCHEMBL30294165 0.96 MC4R (0.51) MC4RKISS1RCTSLCTSSCTSK
SCHEMBL30294161 0.96 MC4R (0.51) MC4RKISS1RCTSLCTSSCTSK
SCHEMBL30294166 0.96 MC4R (0.51) MC4RKISS1RCTSLCTSSCTSK
SCHEMBL30294167 0.96 MC4R (0.51) MC4RKISS1RCTSLCTSSCTSK
SCHEMBL29717261 0.96 MC4R (0.51) MC4RKISS1RCTSLCTSSCTSK
SCHEMBL22330634 0.92 QRFPR (0.48) MC4RKISS1RCTSLCTSSCTSK
SCHEMBL20045525 0.92 QRFPR (0.48) MC4RKISS1RCTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11591367-B2 Melanocortin-1-receptor agonists DSM IP ASSETS B.V. (NL) 2023-02-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11591367-B2 Melanocortin-1-receptor agonists MC1R, MC3R, MC5R MC4R 4/4885KISS1R 36/4885CTSL 1272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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