Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 4/20 | 0.81 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.81 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.46 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27420465 | 1.00 | EDNRA (0.81) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL31017594 | 0.94 | EDNRA (0.81) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL6539684 | 0.92 | EDNRA (0.89) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL6484488 | 0.92 | EDNRA (0.87) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL29706543 | 0.92 | EDNRA (0.87) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL5791243 | 0.92 | EDNRA (0.87) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL6540125 | 0.91 | EDNRA (0.89) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL5534811 | 0.91 | EDNRA (0.84) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL6540544 | 0.91 | EDNRA (0.84) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL15721470 | 0.91 | EDNRA (0.86) | EDNRAAGTR1AGTR2ACHELTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393920-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023025277-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |