Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 4/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29584356 | 1.00 | CYP4F2 (0.38) | CYP4F2CYP4A11CFTRRORCKDM5A | |
| SCHEMBL29243764 | 1.00 | CYP4F2 (0.38) | CYP4F2CYP4A11CFTRRORCKDM5A | |
| SCHEMBL24424213 | 1.00 | CYP4F2 (0.38) | CYP4F2CYP4A11CFTRRORCKDM5A | |
| SCHEMBL24424191 | 0.88 | CFTR (0.37) | CFTRKDM5ATLR9TLR8TLR7 | |
| SCHEMBL24423092 | 0.88 | CFTR (0.37) | CFTRKDM5ATLR9TLR8TLR7 | |
| SCHEMBL29584668 | 0.88 | CFTR (0.37) | CFTRKDM5ATLR9TLR8TLR7 | |
| SCHEMBL24423984 | 0.88 | CFTR (0.37) | CFTRKDM5ATLR9TLR8TLR7 | |
| SCHEMBL24424175 | 0.87 | FFAR4 (0.36) | CYP4F2CYP4A11HCRTR2TBK1CCNT1 | |
| SCHEMBL29243425 | 0.87 | FFAR4 (0.36) | CYP4F2CYP4A11HCRTR2TBK1CCNT1 | |
| SCHEMBL29584172 | 0.87 | FFAR4 (0.36) | CYP4F2CYP4A11HCRTR2TBK1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230062861-A1 | PPARg MODULATORS AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230062861-A1 | PPARg MODULATORS AND METHODS OF USE | PPARG, PPARA, PPARD | CYP4F2 290/4885CYP4A11 75/4885CFTR 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.