Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.73 |
| ▸ | CD63 | P08962 | 6/20 | 0.73 |
| ▸ | JAK2 | O60674 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25292590 | 1.00 | SYK (0.73) | SYKCD63JAK2 | |
| SCHEMBL25797068 | 0.90 | SYK (0.59) | SYKCD63JAK2 | |
| SCHEMBL30299467 | 0.85 | SYK (0.63) | SYKCD63JAK2 | |
| SCHEMBL25249235 | 0.85 | SYK (0.63) | SYKCD63JAK2 | |
| Lanraplenib SCHEMBL16820581 | 0.85 | SYK (1.00) | SYKCD63JAK2 | |
| Lanraplenib SCHEMBL29422916 | 0.85 | SYK (1.00) | SYKCD63JAK2 | |
| SCHEMBL25799571 | 0.81 | SYK (0.51) | SYKCD63JAK2 | |
| SCHEMBL25797064 | 0.81 | SYK (0.50) | SYKCD63JAK2 | |
| SCHEMBL31010502 | 0.80 | SYK (0.49) | SYKCD63JAK2 | |
| Lanraplenib SCHEMBL16820593 | 0.80 | SYK (0.89) | SYKCD63JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157848-A1 | COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS | Nanjing Ruijie Pharma Co., Ltd. (CN) | 2023-04-05 | — | — | EP | claimed |
| CN-115916782-A | Compounds and their use as spleen tyrosine kinase inhibitors | 南京瑞捷医药科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115916782-B | Compounds and their use as inhibitors of spleen tyrosine kinase | 南京瑞捷医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| EP-4157848-A1 | COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS | Nanjing Ruijie Pharma Co., Ltd. (CN) | 2023-04-05 | — | — | EP | disclosed |
| CN-115916782-A | Compounds and their use as spleen tyrosine kinase inhibitors | 南京瑞捷医药科技有限公司 | 2023-04-04 | — | — | CN | disclosed |