Dicyclohexylcarbodiimide

Dicyclohexylcarbodiimide

SCHEMBL303

C(=NC1CCCCC1)=NC1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 1.00
HIF1A Q16665 1/20 1.00
ALDH1A1 P00352 1/20 0.60
CYP1A2 P05177 1/20 0.42
APLNR P35414 1/20 0.38
SIGMAR1 Q99720 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15667923 1.00 EPHX1 (1.00) EPHX1HIF1AALDH1A1CYP1A2APLNR
Dicyclohexylcarbodiimide SCHEMBL3173433 1.00 EPHX1 (1.00) EPHX1HIF1AALDH1A1CYP1A2APLNR
SCHEMBL11842065 1.00 EPHX1 (1.00) EPHX1HIF1AALDH1A1CYP1A2APLNR
SCHEMBL21986399 1.00 EPHX1 (1.00) EPHX1HIF1AALDH1A1CYP1A2APLNR
Dicyclohexylcarbodiimide SCHEMBL28535893 0.97 EPHX1 (0.94) EPHX1HIF1AALDH1A1CYP1A2APLNR
Dicyclohexylcarbodiimide SCHEMBL22804053 0.97 EPHX1 (0.94) EPHX1HIF1AALDH1A1CYP1A2APLNR
Dicyclohexylcarbodiimide SCHEMBL6931632 0.97 EPHX1 (0.94) EPHX1HIF1AALDH1A1CYP1A2APLNR
Dicyclohexylcarbodiimide SCHEMBL1073570 0.97 EPHX1 (0.94) EPHX1HIF1AALDH1A1CYP1A2APLNR
Dicyclohexylcarbodiimide SCHEMBL28399447 0.97 EPHX1 (0.94) EPHX1HIF1AALDH1A1CYP1A2APLNR
SCHEMBL1290378 0.97 EPHX1 (0.93) EPHX1HIF1AALDH1A1CYP1A2APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 234878 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080117-A Preparation method of N-fluorenylmethoxycarbonyl-O-tert-butyl-L-threonine-phenylalanine 2026-05-26 CN claimed
CN-122080119-A Synthesis method of MC-Gly-Gly-Phe-Gly tetrapeptide linker 2026-05-26 CN claimed
CN-122074591-A Novel feed for replacing corn 2026-05-26 CN claimed
CN-122080590-A High-heat-conductivity low-water-absorption epoxy molding compound for semiconductors 2026-05-26 CN claimed
CN-122080417-A Cast-in-place concrete hydration heat optimal control method for lock mass concrete structure 2026-05-26 CN claimed
CN-118026984-B Rhodamine B modified lysine derivative and synthetic method and application thereof HEFEI UNIVERSITY OF TECHNOLOGY (CN) 2026-05-26 CN claimed
CN-122080485-A Preparation method of polyimide-based phase-change aerogel 2026-05-26 CN claimed
CN-122080614-A PEG/PEI nanocomposite based on carboxymethyl cellulose and preparation method and application thereof 2026-05-26 CN claimed
CN-117638405-B Diaphragm with chelating function and preparation method and application thereof Gotion High-tech Co., Ltd. (CN) 2026-05-26 CN claimed
CN-122080038-A Arylboron compound, preparation method and application thereof, and pharmaceutical composition 2026-05-26 CN claimed
US-4012464-A S-(2-diisopropylamino-ethyl)O-ethyl methylphosphonothioate stabilized with soluble carbodiimides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1977-03-15 US claimed
US-4008270-A Process for preparing 2-(substituted phenyl)propionic acids THE UPJOHN COMPANY (US) 1977-02-15 US claimed
US-4005074-A Process for cleaving an imido side chain from penicillins and cephalosporins ELI LILLY AND COMPANY (US) 1977-01-25 US claimed
US-3998836-A CONDENSATION OF A DIAMINO-MALEONITRILE AND AN AROMATIC ALPHA-KETONE; HERBICIDES SAGAMI CHEMICAL RESEARCH CENTER (JA) 1976-12-21 US claimed
US-3998811-A SEDATIVES, TRANQUILIZERS; AMIDATION, CYCLIZATION, HYDROLYSIS CRC COMPAGNIA DI RECERCA CHIMICA S.A. (CH) 1976-12-21 US claimed
US-3997525-A Tetra-125 iodo-di-tyramine of digitalis derivative and process for making the same BIO-TEC, INC. (US) 1976-12-14 US claimed
US-3996268-A CARBONYL-BIS (L-METHIONINE P-NITROPHENYL ESTER) AND DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1976-12-07 US claimed
US-3988307-A ATTACHING AN ALPHA,BETA-UNSATURATED AMINO ACID TO A SOLID SUPPORT; ACIDIC AQUEOUS RELEASE AGENT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1976-10-26 US claimed
US-3980433-A HYDROXYLAMINE, CARBODIIMIDE TO FORM HYDROXAMIC ACID TAMURA ZENZO 1976-09-14 US claimed
US-3953417-A Synthetically modified trypsin inhibitors and process for preparing them HOECHST AKTIENGESELLSCHAFT (DT) 1976-04-27 US claimed