Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.81 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14121407 | 0.90 | PPARG (1.00) | PPARGPPARAAGTR1 | |
| SCHEMBL18475308 | 0.88 | PPARG (0.79) | PPARGPPARAAGTR1 | |
| SCHEMBL14240622 | 0.87 | PPARG (0.85) | PPARGPPARAAGTR1 | |
| SCHEMBL14211133 | 0.87 | PPARG (0.79) | PPARGPPARA | |
| SCHEMBL14121063 | 0.86 | PPARG (0.81) | PPARGPPARAAGTR1 | |
| SCHEMBL30300757 | 0.86 | PPARG (0.81) | PPARGPPARAAGTR1 | |
| SCHEMBL16125423 | 0.86 | PPARG (0.59) | PPARGPPARAAGTR1 | |
| SCHEMBL16125506 | 0.86 | PPARG (0.59) | PPARGPPARAAGTR1 | |
| SCHEMBL14120280 | 0.85 | PPARG (0.59) | PPARG | |
| SCHEMBL14211131 | 0.85 | PPARG (0.82) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240009169-A9 | PPARG Modulators for the Treatment of Osteoporosis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-01-11 | — | — | US | disclosed |
| US-20230072933-A1 | PPARG Modulators for the Treatment of Osteoporosis | SCRIPPS RESEARCH INST (US) | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230072933-A1 | PPARG Modulators for the Treatment of Osteoporosis | PPARG, PPARA, PPARD | PPARG 1/4885PPARA 2/4885AGTR1 1675/4885 |
| US-20240009169-A9 | PPARG Modulators for the Treatment of Osteoporosis | PPARG, PPARA, PPARD | PPARG 1/4885PPARA 2/4885AGTR1 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.