SCHEMBL30301802

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17845975	1.00	EGFR (0.67)	EGFRERBB2CD38KDM4EMEN1
	SCHEMBL29793189	0.89	EGFR (0.73)	EGFRERBB2CD38KDM4EMEN1
	SCHEMBL17858692	0.89	EGFR (0.73)	EGFRERBB2CD38KDM4EMEN1
	SCHEMBL17845933	0.87	EGFR (0.61)	EGFRERBB2CD38KDM4EMEN1
	SCHEMBL30301804	0.86	EGFR (0.69)	EGFRERBB2CD38KDM4EMEN1
	SCHEMBL17845934	0.86	EGFR (0.69)	EGFRERBB2CD38KDM4EMEN1
	SCHEMBL17845917	0.85	EGFR (0.69)	EGFRERBB2CD38RAF1BRAF
	SCHEMBL29667032	0.85	EGFR (0.69)	EGFRERBB2CD38RAF1BRAF
	SCHEMBL4738831	0.84	EGFR (0.70)	EGFRERBB2CD38KDM4EMEN1
	SCHEMBL4787908	0.84	EGFR (0.82)	EGFRERBB2CD38KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.