Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25393523 | 0.93 | EPHX2 (0.48) | EPHX2PPARGKMT2AMEN1ALDH1A1 | |
| SCHEMBL25393273 | 0.92 | EPHX2 (0.50) | EPHX2KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL24435448 | 0.89 | CNR1 (0.44) | EPHX2 | |
| SCHEMBL28702300 | 0.88 | CACNA2D1 (0.45) | EPHX2KMT2AMEN1 | |
| SCHEMBL25395413 | 0.86 | EPHX2 (0.41) | EPHX2PPARGGRM2 | |
| SCHEMBL28700042 | 0.85 | FEN1 (0.43) | EPHX2 | |
| SCHEMBL25392115 | 0.85 | EPHX2 (0.39) | EPHX2PPARGKMT2AMEN1ALDH1A1 | |
| SCHEMBL25393933 | 0.83 | CNR1 (0.46) | EPHX2PPARG | |
| SCHEMBL25393757 | 0.82 | EPHX2 (0.42) | EPHX2PPARGKMT2AMEN1ALDH1A1 | |
| SCHEMBL25394598 | 0.81 | EPHX2 (0.40) | EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925606-A | 5- (3- (sulfonamido) phenyl) -1H-pyrrole-2-carboxylic acid derivative and preparation method and application thereof | 宁夏医科大学 | 2023-04-07 | — | — | CN | claimed |
| CN-115925606-B | 5- (3- (sulfonamide) phenyl) -1H-pyrrole-2-carboxylic acid derivative and preparation method and application thereof | 宁夏医科大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-115925606-A | 5- (3- (sulfonamido) phenyl) -1H-pyrrole-2-carboxylic acid derivative and preparation method and application thereof | 宁夏医科大学 | 2023-04-07 | — | — | CN | disclosed |