Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | F7 | P08709 | 5/20 | 0.49 |
| ▸ | F3 | P13726 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30457561 | 0.90 | MAPT (0.60) | PPARAALDH1A1F7F3PPARG | |
| SCHEMBL10993370 | 0.86 | EPHX2 (0.54) | ALDH1A1MAPTLMNARXFP1EPHX2 | |
| SCHEMBL10993373 | 0.86 | EPHX2 (0.54) | ALDH1A1MAPTLMNARXFP1EPHX2 | |
| SCHEMBL6758781 | 0.82 | EPHX2 (0.52) | MAPTLMNARXFP1EPHX2FAAH | |
| SCHEMBL6758777 | 0.82 | EPHX2 (0.52) | MAPTLMNARXFP1EPHX2FAAH | |
| SCHEMBL23925403 | 0.80 | TSHR (0.67) | PPARAALDH1A1F7F3PPARG | |
| SCHEMBL11443984 | 0.80 | TSHR (0.67) | PPARAALDH1A1F7F3PPARG | |
| SCHEMBL11437841 | 0.80 | TSHR (0.67) | PPARAALDH1A1F7F3PPARG | |
| SCHEMBL23925457 | 0.80 | TSHR (0.67) | PPARAALDH1A1F7F3PPARG | |
| SCHEMBL23925402 | 0.80 | TSHR (0.67) | PPARAALDH1A1F7F3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4402121-A1 | ACYCLIC LIPIDS AND METHODS OF USE THEREOF | Renagade Therapeutics Management Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| WO-2023044343-A1 | ACYCLIC LIPIDS AND METHODS OF USE THEREOF | RENAGADE THERAPEUTICS MANAGEMENT INC. (US) | 2023-03-23 | — | — | WO | disclosed |