SCHEMBL3030442

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3030445	1.00	PIM1 (0.40)	PIM1PIM2BRD4ATAD2HRH4
	SCHEMBL1277522	0.85	BRD4 (0.38)	BRD4ATAD2JAK3JAK2JAK1
	SCHEMBL1277526	0.85	BRD4 (0.38)	BRD4ATAD2JAK3JAK2JAK1
	SCHEMBL1277527	0.85	BRD4 (0.38)	BRD4ATAD2JAK3JAK2JAK1
	SCHEMBL1277660	0.82	BRD4 (0.43)	PIM1PIM2BRD4ATAD2
	SCHEMBL1277663	0.82	BRD4 (0.43)	PIM1PIM2BRD4ATAD2
	SCHEMBL3018683	0.81	JAK1 (0.37)	PIM1PIM2BRD4ATAD2JAK3
	SCHEMBL3018677	0.81	JAK1 (0.37)	PIM1PIM2BRD4ATAD2JAK3
	SCHEMBL1277593	0.80	BRD4 (0.41)	PIM1PIM2BRD4ATAD2JAK3
	SCHEMBL1277596	0.80	BRD4 (0.41)	PIM1PIM2BRD4ATAD2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.