Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.55 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | SLC6A15 | Q9H2J7 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030449 | 1.00 | HRH1 (0.55) | HRH1PTAFRSLC6A15MAPTMEN1 | |
| SCHEMBL3701651 | 0.93 | HRH1 (0.55) | HRH1PTAFRSLC6A15MAPTMEN1 | |
| SCHEMBL3701654 | 0.93 | HRH1 (0.55) | HRH1PTAFRSLC6A15MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL3040291 | 0.92 | MAPK1 (0.52) | HRH1PTAFRMAPTMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL3040296 | 0.92 | MAPK1 (0.52) | HRH1PTAFRMAPTMEN1MAPK1 | |
| SCHEMBL3037172 | 0.91 | MEN1 (0.45) | HRH1PTAFRSLC6A15MAPTMEN1 | |
| SCHEMBL3037169 | 0.91 | MEN1 (0.45) | HRH1PTAFRSLC6A15MAPTMEN1 | |
| SCHEMBL3704516 | 0.89 | HRH1 (0.58) | HRH1PTAFRSLC6A15MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL3041320 | 0.88 | MEN1 (0.41) | HRH1PTAFRMAPTMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL3041316 | 0.88 | MEN1 (0.41) | HRH1PTAFRMAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460803-B1 | METHOD FOR PRODUCING THIABENZOAZULENE PROPIONIC ACID DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2016-01-13 | — | — | EP | disclosed |
| EP-2243778-B1 | PIPERIDINE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2014-10-29 | — | — | EP | disclosed |
| US-8536342-B2 | Process for producing thiabenzoazulene-propionic acid derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-09-17 | — | — | US | disclosed |
| EP-2460803-A1 | METHOD FOR PRODUCING THIABENZOAZULENE PROPIONIC ACID DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-20120123127-A1 | PROCESS FOR PRODUCING THIABENZOAZULENE-PROPIONIC ACID DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| EP-2243778-A1 | PIPERIDINE DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2010-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123127-A1 | PROCESS FOR PRODUCING THIABENZOAZULENE-PROPIONIC ACID DERIVATIVE | HRH4, HRH2, HRH1 | HRH1 3/4885PTAFR 31/4885SLC6A15 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.