Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.68 |
| ▸ | DDB1 | Q16531 | 19/20 | 0.68 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392916 | 1.00 | CRBN (0.68) | CRBNDDB1IKZF3 | |
| SCHEMBL30392434 | 1.00 | CRBN (0.68) | CRBNDDB1IKZF3 | |
| SCHEMBL30391734 | 1.00 | CRBN (0.68) | CRBNDDB1IKZF3 | |
| SCHEMBL25123851 | 1.00 | CRBN (0.68) | CRBNDDB1IKZF3 | |
| SCHEMBL25123420 | 1.00 | CRBN (0.68) | CRBNDDB1IKZF3 | |
| SCHEMBL23832528 | 1.00 | CRBN (0.68) | CRBNDDB1IKZF3 | |
| SCHEMBL23842262 | 1.00 | CRBN (0.68) | CRBNDDB1IKZF3 | |
| SCHEMBL25123805 | 1.00 | CRBN (0.68) | CRBNDDB1IKZF3 | |
| SCHEMBL22776655 | 1.00 | CRBN (0.68) | CRBNDDB1IKZF3 | |
| SCHEMBL26634963 | 1.00 | CRBN (0.68) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023055952-A1 | NEUROTROPHIC TYROSINE RECEPTOR KINASE (NTRK) DEGRADING COMPOUNDS | C4 THERAPEUTICS, INC. (US) | 2023-04-06 | — | — | WO | disclosed |