SCHEMBL30307447

SCHEMBL30307447

O=C(O)c1ccc(Oc2cccc(C(=O)O)c2)cc1

nearest known ligand 0.85

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.85
KMO O15229 1/20 0.70
KDM4E B2RXH2 1/20 0.69
SRD5A2 P31213 3/20 0.67
PARP15 Q460N3 2/20 0.66
PARP10 Q53GL7 2/20 0.66
TNKS O95271 1/20 0.66
PARP14 Q460N5 1/20 0.66
TNKS2 Q9H2K2 1/20 0.66
PARP2 Q9UGN5 1/20 0.66
POLB P06746 2/20 0.63
NPC1 O15118 2/20 0.63
CYP2C9 P11712 1/20 0.63
RAB9A P51151 1/20 0.63
NR1H4 Q96RI1 1/20 0.62
HDAC8 Q9BY41 1/20 0.59
MRGPRX4 Q96LA9 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70012 1.00 AKR1C3 (0.85) AKR1C3KMOKDM4ESRD5A2PARP15
SCHEMBL16429240 1.00 AKR1C3 (0.85) AKR1C3KMOKDM4ESRD5A2PARP15
SCHEMBL16429487 0.98 AKR1C3 (0.82) AKR1C3KMOKDM4ESRD5A2PARP15
Hydrochloric Acid SCHEMBL7137782 0.98 AKR1C3 (0.82) AKR1C3KMOKDM4ESRD5A2PARP15
SCHEMBL1042631 0.96 AKR1C3 (0.92) AKR1C3KMOKDM4ESRD5A2PARP15
SCHEMBL30266789 0.96 AKR1C3 (0.92) AKR1C3KMOKDM4ESRD5A2PARP15
SCHEMBL4320685 0.94 AKR1C3 (0.96) AKR1C3KMOKDM4ESRD5A2PARP15
SCHEMBL29546656 0.94 AKR1C3 (0.96) AKR1C3KMOKDM4ESRD5A2PARP15
SCHEMBL28701196 0.94 AKR1C3 (0.96) AKR1C3KMOKDM4ESRD5A2PARP15
SCHEMBL10497003 0.93 AKR1C3 (0.79) AKR1C3KMOKDM4ESRD5A2PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924699-A Polyimide precursor and polyimide resin composition 旭化成株式会社 2024-04-26 CN disclosed
CN-113874419-B Polyimide precursor and polyimide resin composition 旭化成株式会社 2024-01-09 CN disclosed
CN-111479854-B Polyimide precursor resin composition 旭化成株式会社 2023-05-09 CN disclosed