Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23887386 | 1.00 | PIK3CA (0.38) | PIK3CAPDE2A | |
| SCHEMBL26662684 | 1.00 | PIK3CA (0.38) | PIK3CAPDE2A | |
| SCHEMBL31316391 | 1.00 | PIK3CA (0.38) | PIK3CAPDE2A | |
| SCHEMBL26881034 | 0.89 | PIK3CA (0.36) | PIK3CA | |
| SCHEMBL27136581 | 0.89 | PIK3CA (0.36) | PIK3CA | |
| SCHEMBL23887408 | 0.89 | PIK3CA (0.36) | PIK3CA | |
| SCHEMBL30584413 | 0.89 | PIK3CA (0.36) | PIK3CA | |
| SCHEMBL26880753 | 0.89 | PIK3CA (0.36) | PIK3CA | |
| SCHEMBL27008317 | 0.87 | PIK3CA (0.45) | PIK3CAPDE2A | |
| SCHEMBL27126273 | 0.87 | PIK3CA (0.45) | PIK3CAPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115956075-A | Allosteric enone inhibitors of phosphoinositide 3-kinases (PI 3 ks) for the treatment of diseases associated with PI3K modulation | 佩特拉制药公司 | 2023-04-11 | — | — | CN | disclosed |