Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 14/20 | 0.52 |
| ▸ | PRKDC | P78527 | 7/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23887000 | 1.00 | PIK3CA (0.52) | PIK3CAPRKDCPIK3CBPIK3CDPIK3CG | |
| SCHEMBL23886928 | 0.96 | PIK3CA (0.56) | PIK3CAPRKDCPIK3CBPIK3CDPIK3CG | |
| SCHEMBL23887066 | 0.88 | PRKDC (0.45) | PIK3CAPRKDCPIK3CBPIK3CDPIK3CG | |
| SCHEMBL30307540 | 0.88 | PRKDC (0.45) | PIK3CAPRKDCPIK3CBPIK3CDPIK3CG | |
| SCHEMBL23887278 | 0.88 | PRKDC (0.50) | PIK3CAPRKDCPIK3CBPIK3CDPIK3CG | |
| SCHEMBL23887303 | 0.87 | PIK3CA (0.47) | PIK3CAPRKDCPIK3CBPIK3CDPIK3CG | |
| SCHEMBL23887166 | 0.87 | PIK3CA (0.46) | PIK3CAPRKDCPIK3CBPIK3CDPIK3CG | |
| SCHEMBL23887064 | 0.87 | PIK3CA (0.53) | PIK3CAPRKDC | |
| SCHEMBL23887310 | 0.84 | PIK3CA (0.59) | PIK3CAPRKDCPIK3CBPIK3CDPIK3CG | |
| SCHEMBL23887139 | 0.83 | PIK3CA (0.43) | PIK3CAPRKDCPIK3CBPIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115956075-A | Allosteric enone inhibitors of phosphoinositide 3-kinases (PI 3 ks) for the treatment of diseases associated with PI3K modulation | 佩特拉制药公司 | 2023-04-11 | — | — | CN | disclosed |