Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30309207 | 0.94 | GRM5 (0.47) | GRM5MAP3K14PIM1TRPV1 | |
| SCHEMBL19859465 | 0.82 | GRM5 (0.50) | GRM5TRPV1 | |
| SCHEMBL28621555 | 0.77 | GRM5 (0.43) | GRM5TRPV1 | |
| Formic Acid SCHEMBL30309196 | 0.76 | GRM5 (0.54) | GRM5 | |
| SCHEMBL14476027 | 0.74 | GRM5 (0.48) | GRM5 | |
| SCHEMBL29990900 | 0.71 | MAP3K14 (0.37) | MAP3K14PIM1 | |
| SCHEMBL382392 | 0.68 | GRM5 (0.51) | GRM5 | |
| SCHEMBL22048899 | 0.68 | GRM5 (0.51) | GRM5 | |
| SCHEMBL852827 | 0.68 | GRM5 (0.51) | GRM5 | |
| SCHEMBL14476025 | 0.68 | GRM5 (0.48) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161937-A1 | PYRIDO[2,3-B] [1,4] OXAZINES OR TETRAHYDROPYRIDO[2,3-B][1,4] OXAZEPINES AS IAP ANTAGONISTS | BeiGene, Ltd. (KY) | 2023-04-12 | — | — | EP | disclosed |