SCHEMBL30309461

SCHEMBL30309461

CN1CCN(C(=O)c2ccc(N)cc2F)CC1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CPS1 P31327 2/20 0.56
EPHX2 P34913 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
HRH4 Q9H3N8 5/20 0.52
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
KDM4E B2RXH2 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MTOR P42345 2/20 0.46
HSP90AA1 P07900 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3396511 1.00 CPS1 (0.56) CPS1EPHX2MEN1KMT2AHRH4
SCHEMBL17400790 0.94 CPS1 (0.58) CPS1EPHX2MEN1KMT2AHRH4
SCHEMBL3400169 0.88 MEN1 (0.57) CPS1EPHX2MEN1KMT2AHRH4
SCHEMBL4724651 0.86 CPS1 (0.56) CPS1MEN1KMT2ALMNAALOX15
SCHEMBL2306539 0.84 HRH4 (0.55) MEN1KMT2AHRH4LMNATP53
SCHEMBL13841322 0.84 KDM4E (0.63) CPS1EPHX2MEN1KMT2AHRH4
SCHEMBL30198967 0.84 CPS1 (0.52) CPS1HRH4LMNAKDM4EMTOR
SCHEMBL21245769 0.84 CPS1 (0.52) CPS1HRH4LMNAKDM4EMTOR
SCHEMBL23748561 0.84 CPS1 (0.48) CPS1EPHX2KMT2ATSHRKDM4E
SCHEMBL34472312 0.83 CPS1 (0.46) CPS1EPHX2MEN1KMT2AHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109690-A1 HDAC6 INHIBITORS AND METHOD OF THEIR USE BAERENKRAFT THERAPEUTICS LLC (US) 2026-04-23 US disclosed
WO-2024245406-A1 1H-[1,2,3]TRIAZOLO[4,5-H]QUINAZOLINE COMPOUNDS AS PROTEIN KINASE INHIBITORS 成都赛璟生物医药科技有限公司 2024-12-05 WO disclosed
CN-111377907-B Polysubstituted phenylamino pyrimidine derivative and preparation method and application thereof 杭州百新生物医药科技有限公司 2023-03-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109690-A1 HDAC6 INHIBITORS AND METHOD OF THEIR USE HDAC6, HDAC3, HDAC1 CPS1 2613/4885EPHX2 3702/4885MEN1 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.