Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24447653 | 0.90 | FLT3 (0.66) | FLT3HRH4KMT2AMEN1RCE1 | |
| SCHEMBL29394458 | 0.90 | FLT3 (0.66) | FLT3HRH4KMT2AMEN1RCE1 | |
| SCHEMBL7979026 | 0.82 | FLT3 (0.68) | FLT3HRH4KMT2AMEN1RCE1 | |
| SCHEMBL913914 | 0.82 | FLT3 (0.68) | FLT3HRH4KMT2AMEN1RCE1 | |
| SCHEMBL29414307 | 0.82 | FLT3 (0.68) | FLT3HRH4KMT2AMEN1RCE1 | |
| SCHEMBL217459 | 0.81 | FLT3 (0.66) | FLT3HRH4KMT2AMEN1RCE1 | |
| SCHEMBL24113092 | 0.81 | FLT3 (0.66) | FLT3HRH4KMT2AMEN1RCE1 | |
| SCHEMBL30310403 | 0.81 | FLT3 (0.66) | FLT3HRH4KMT2AMEN1RCE1 | |
| SCHEMBL23835764 | 0.78 | FLT3 (0.63) | FLT3HRH4KMT2AMEN1RCE1 | |
| SCHEMBL24019713 | 0.78 | IDO1 (0.64) | FLT3HRH4KMT2AMEN1RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |